Oxalic Acid

Oxalic Acid

SCHEMBL7613486

CCCCCC(C)Oc1nsnc1C1=CCCN(C)C1.O=C(O)C(=O)O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 known ✓ P31645 1/20 0.61
CHRM1 P11229 4/20 0.62
CHRM2 P08172 1/20 0.61
CHRM4 P08173 1/20 0.61
HTR1A P08908 1/20 0.61
CHRM5 P08912 1/20 0.61
ADRA2A P08913 1/20 0.61
CHRM3 P20309 1/20 0.61
MAOA P21397 1/20 0.61
DRD1 P21728 1/20 0.61
ACHE P22303 1/20 0.61
SLC6A2 P23975 1/20 0.61
PDE4A P27815 1/20 0.61
ADRA1A P35348 1/20 0.61
DRD3 P35462 1/20 0.61
HTR2B P41595 1/20 0.61
SLC6A3 Q01959 1/20 0.61
KCNH2 Q12809 1/20 0.61
CACNA1C Q13936 1/20 0.61
SCN5A Q14524 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6917201 0.94 CHRM1 (0.70) CHRM1CHRM2CHRM4HTR1ACHRM5
SCHEMBL6911613 0.91 CHRM1 (0.69) CHRM1CHRM2CHRM4HTR1ACHRM5
Fumaric Acid SCHEMBL7613465 0.90 CHRM1 (0.59) CHRM1CHRM2CHRM4HTR1ACHRM5
Fumaric Acid SCHEMBL7613470 0.90 CHRM1 (0.59) CHRM1CHRM2CHRM4HTR1ACHRM5
Oxalic Acid SCHEMBL7613627 0.85 CHRM1 (0.87) CHRM1CHRM2CHRM4HTR1ACHRM5
Oxalic Acid SCHEMBL7611848 0.84 CHRM1 (0.66) CHRM1CHRM4
Oxalic Acid SCHEMBL7621656 0.84 CHRM1 (0.87) CHRM1CHRM2CHRM4HTR1ACHRM5
Xanomeline SCHEMBL6911783 0.84 CHRM1 (0.87) CHRM1CHRM2CHRM4HTR1ACHRM5
Oxalic Acid SCHEMBL7616095 0.84 CHRM1 (0.87) CHRM1CHRM2CHRM4HTR1ACHRM5
SCHEMBL7900579 0.83 CHRM1 (0.72) CHRM1CHRM2CHRM4HTR1ACHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0734259-B1 Use of piperidine compounds in the treatment of schizophrenia NOVO NORDISK AS (DK) 2002-06-12 EP disclosed
US-5773452-A ALZHEIMER'S DISEASE; COGNITION ACTIVATORS NOVO NORDISK ALS (DK) 1998-06-30 US disclosed
US-5753683-A SCHIZOPHRENIA NOVO NORDISK A/S (DK) 1998-05-19 US disclosed
US-5750541-A 3-(1,2,5-THIA OR OXADIAZOL-3-YL)-1,2,5,6-PYRIDINE DERIVATIVES; SCHIZOPHRENIFORM DISEASES; SIDE EFFECT REDUCTION NOVO NORDISK A/S (DK) 1998-05-12 US disclosed
US-5744489-A ADMINISTERING CERTAIN 1,2,5-THIADIAZOLE AND 1,2,5-OXADIAZOLE COMPOUNDS GREENWOOD BEVERLEY (US) 1998-04-28 US disclosed
US-5565475-A Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives MUHLHAUSER MARK A (US) 1996-10-15 US disclosed
EP-0732925-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1996-09-25 EP disclosed
US-5545638-A USING A 3-(TETRAHYDROPYRID-3-YL-) SUBSTITUTED (OXA- OR THIA-)DIAZOLE COMPOUND NOVO NORDISK A/S (DK) 1996-08-13 US disclosed
WO-1995017185-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1995-06-29 WO disclosed