Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614519 | 1.00 | FGFR1 (0.43) | FGFR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL7611062 | 0.89 | TUBB1 (0.49) | ALDH1A1GAAMAPTHTTNPSR1 | |
| SCHEMBL7611067 | 0.89 | TUBB1 (0.49) | ALDH1A1GAAMAPTHTTNPSR1 | |
| SCHEMBL7608252 | 0.87 | TUBB1 (0.52) | FGFR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL7608249 | 0.87 | TUBB1 (0.52) | FGFR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL7551160 | 0.83 | TUBB1 (0.58) | FGFR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL7551155 | 0.83 | TUBB1 (0.58) | FGFR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL7617918 | 0.82 | TUBB1 (0.53) | FGFR1ALDH1A1MAPTTUBB1LMNA | |
| SCHEMBL7617923 | 0.82 | TUBB1 (0.53) | FGFR1ALDH1A1MAPTTUBB1LMNA | |
| SCHEMBL6603346 | 0.81 | APP (0.43) | GAATUBB1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143064-A1 | Novel use of compounds of the chalcones class | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | US | claimed |
| US-20020143064-A1 | Novel use of compounds of the chalcones class | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143064-A1 | Novel use of compounds of the chalcones class | NR2E1, FLT1, KDR | FGFR1 252/4885ALDH1A1 1815/4885GAA 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.