SCHEMBL76147

SCHEMBL76147

Cc1ccccc1-c1ccc(-c2ccc(-c3ccccc3)cc2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ESR2 Q92731 1/20 0.48
MEN1 O00255 1/20 0.48
APAF1 O14727 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
XBP1 P17861 1/20 0.48
PTBP1 P26599 1/20 0.48
HTT P42858 1/20 0.48
GALK1 P51570 1/20 0.48
BLM P54132 1/20 0.48
SMAD3 P84022 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CA12 O43570 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431901 1.00 NPC1 (0.48) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL9792865 1.00 NPC1 (0.48) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL16192737 0.86 ESR2 (0.63) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL5013854 0.86 ESR2 (0.63) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL14508143 0.85 MEN1 (0.50) NPC1RAB9ASMN1; SMN2MEN1MAPT
SCHEMBL20684723 0.84 PDE3B (0.50) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL10390024 0.84 ESR2 (0.48) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL21250647 0.84 ESR2 (0.47) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL22923706 0.83 ESR2 (0.46) NPC1RAB9ASMN1; SMN2ESR2MEN1
SCHEMBL19920853 0.83 ESR2 (0.50) NPC1RAB9ASMN1; SMN2ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4421115-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
EP-4421114-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
US-11339263-B2 Fibrillated polymer compositions and methods of their manufacture SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-24 US claimed
CN-107406694-B Luminescent silicone coating 莫门蒂夫性能材料股份有限公司 2020-06-26 CN claimed
EP-3092082-B1 ARTICLE WITH REDUCED ABSORBANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-12-12 EP claimed
US-20180056635-A1 ARTICLE WITH REDUCED ABSORBANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-03-01 US claimed
US-20170369715-A1 LUMINESCENT SILICONE COATINGS MOMENTIVE PERFORMANCE MATERIALS INC. 2017-12-28 US claimed
EP-3240833-A1 LUMINESCENT SILICONE COATINGS Momentive Performance Materials Inc. (US) 2017-11-08 EP claimed
EP-3092082-A1 ARTICLE WITH REDUCED ABSORBANCE SABIC Global Technologies B.V. (NL) 2016-11-16 EP claimed
WO-2016147119-A1 ARTICLE WITH REDUCED ABSORBANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-22 WO claimed
WO-2016109542-A1 LUMINESCENT SILICONE COATINGS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-07-07 WO claimed
US-6538725-B2 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2003-03-25 US claimed
US-20020135758-A1 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2002-09-26 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
EP-4731711-A2 LIQUID BINDER COMPOSITIONS AND USES THEREOF Acs Technical Products, Inc. (US) 2026-04-29 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
US-20030021998-A1 TAGGING MATERIALS FOR POLYMERS, METHODS, AND ARTICLES MADE THEREBY CITIBANK, N.A., AS COLLATERAL AGENT 2003-01-30 US disclosed
US-6499355-B1 Elongation and cracking testing and optical characterization of small-size coatings and materials GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed
US-6460417-B1 Formability testing of small-size coatings and materials GENERAL ELECTRIC COMPANY 2002-10-08 US disclosed
US-20020135758-A1 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2002-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA NPC1 176/4885RAB9A 597/4885SMN1; SMN2 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.