Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.35 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | INPP5B | P32019 | 2/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616295 | 0.90 | INPPL1 (0.37) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL7615976 | 0.89 | INPPL1 (0.34) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL6395063 | 0.86 | ESR1 (0.48) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL7620812 | 0.80 | ESR1 (0.38) | ESR1ESR2GRM8GRM4 | |
| SCHEMBL6396366 | 0.80 | ESR1 (0.45) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL6401066 | 0.75 | ESR1 (0.51) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL6401534 | 0.75 | HTR2A (0.39) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL6396108 | 0.75 | POLB (0.36) | ESR1ESR2INPPL1INPP5AAKT1 | |
| SCHEMBL28707791 | 0.73 | INPPL1 (0.47) | INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL6401818 | 0.72 | INPPL1 (0.36) | INPPL1INPP5AAKT1INPP5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175425-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000043402-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-27 | — | — | WO | disclosed |