Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614121 | 0.92 | HDAC4 (0.46) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL7620493 | 0.88 | HDAC4 (0.39) | HDAC4MEN1KMT2APGRALDH1A1 | |
| SCHEMBL1573840 | 0.86 | HDAC4 (0.48) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL5163474 | 0.85 | HDAC4 (0.64) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL5165679 | 0.85 | HDAC4 (0.47) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL7722530 | 0.83 | HDAC4 (0.46) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL7722529 | 0.83 | HDAC4 (0.46) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL7617562 | 0.83 | HDAC4 (0.45) | HDAC4MEN1KMT2APGRMAPT | |
| SCHEMBL7612626 | 0.80 | MEN1 (0.65) | HDAC4MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7619694 | 0.79 | MEN1 (0.45) | HDAC4MEN1KMT2APGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-12-04 | — | — | EP | claimed |
| EP-1097139-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-12-04 | — | — | EP | disclosed |