Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.74 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.74 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197154 | 1.00 | ITGAL (0.74) | ITGALITGB2ICAM1 | |
| SCHEMBL6194910 | 0.90 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL7616712 | 0.90 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL6199465 | 0.85 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL6197145 | 0.82 | ITGAL (0.50) | ITGALITGB2ICAM1 | |
| SCHEMBL6308519 | 0.80 | ITGAL (0.81) | ITGALITGB2ICAM1 | |
| SCHEMBL6197120 | 0.80 | ITGAL (0.47) | ITGALITGB2ICAM1 | |
| SCHEMBL6310951 | 0.78 | ITGAL (0.73) | ITGALITGB2ICAM1 | |
| SCHEMBL6317425 | 0.78 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL7612106 | 0.77 | ITGB2 (0.54) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |