Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459574 | 0.93 | EPHX1 (0.47) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL459573 | 0.93 | EPHX1 (0.47) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL476725 | 0.93 | EPHX1 (0.47) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10476064 | 0.92 | EPHX1 (0.46) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL2494231 | 0.88 | EPHX1 (0.55) | SMN1; SMN2NPC1RAB9AEPHX1ACHE | |
| SCHEMBL2494230 | 0.88 | EPHX1 (0.55) | SMN1; SMN2NPC1RAB9AEPHX1ACHE | |
| SCHEMBL16124602 | 0.87 | EPHX1 (0.58) | SMN1; SMN2NPC1RAB9AEPHX1ACHE | |
| SCHEMBL7770681 | 0.87 | EPHX1 (0.58) | SMN1; SMN2NPC1RAB9AEPHX1ACHE | |
| SCHEMBL16124605 | 0.87 | EPHX1 (0.58) | SMN1; SMN2NPC1RAB9AEPHX1ACHE | |
| SCHEMBL7770680 | 0.87 | EPHX1 (0.58) | SMN1; SMN2NPC1RAB9AEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833837-B1 | PROCESS FOR PREPARING DERIVATIVES OF AZABICYCLO NAPHTHYRIDINE CARBOXYLIC ACID COMPRISING A DIPEPTIDE | PFIZER (US) | 2002-07-31 | — | — | EP | disclosed |