Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 2/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616338 | 1.00 | DEPTOR (0.51) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL26512340 | 0.84 | DEPTOR (0.51) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL26512521 | 0.84 | DEPTOR (0.51) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL26513756 | 0.82 | DEPTOR (0.49) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL922086 | 0.78 | DEPTOR (0.61) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL26512485 | 0.75 | MAPT (0.34) | KMT2AKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6637470 | 0.72 | DEPTOR (0.54) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL6479468 | 0.71 | DEPTOR (0.49) | DEPTORTAAR1MEN1KMT2ANPC1 | |
| SCHEMBL922322 | 0.70 | DEPTOR (0.51) | DEPTORTAAR1MEN1KMT2ANOS1 | |
| SCHEMBL922321 | 0.70 | DEPTOR (0.51) | DEPTORTAAR1MEN1KMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436915-B1 | ANTIPROLIFERATIVE AND ANTITUMOR AGENTS AND ANGIOGENESIS INHIBITORS | KINETEK PHARMACEUTICALS, INC. (CA) | 2002-08-20 | — | — | US | disclosed |