SCHEMBL761697

SCHEMBL761697

CN1CCCOC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8272699 0.93
SCHEMBL8357682 0.91 PIK3CD (0.46)
SCHEMBL16498026 0.84
SCHEMBL149594 0.84
Hydrochloric Acid SCHEMBL27484353 0.82
Methylpyrrolidone SCHEMBL27482125 0.79 BRD4 (0.65)
Sulfur Dioxide SCHEMBL28280925 0.78 PIK3CD (0.39)
SCHEMBL12251950 0.76 PIK3CD (0.59)
SCHEMBL28083893 0.76 PIK3CD (0.38)
SCHEMBL24245134 0.75 PIK3CD (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092069-A1 SUBSTITUTED INDAZOLES AS IRAK4 INHIBITORS ASTRAZENECA AB (SE) 2026-04-02 US claimed
EP-3205010-B1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C MOTIVE TECH INC (US) 2026-03-11 EP claimed
US-20240182479-A1 SUBSTITUTED INDAZOLES AS IRAK4 INHIBITORS ASTRAZENECA AB (SE) 2024-06-06 US claimed
EP-4259632-A1 N-(IMIDAZO[1,2-B]PYRIDAZIN-3-YL)-1-CYCLOHEXYL-2H-INDAZOLE-5-CARBOXAMIDE AND N-(PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-1-CYCLOHEXYL-2H-INDAZOLE-5-CARBOXAMIDE DERIVATIVES AS IRAK4 INHIBITORS FOR THE TREATMENT OF ASTHMA Astrazeneca AB (SE) 2023-10-18 EP claimed
CN-116583285-A N- (imidazo [1,2-b ] pyridazin-3-yl) -1-cyclohexyl-2H-indazole-5-carboxamide and N- (pyrazolo [1,5-a ] pyrimidin-3-yl) -1-cyclohexyl-2H-indazole-5-carboxamide derivatives as IRAK4 inhibitors for the treatment of asthma 阿斯利康(瑞典)有限公司 2023-08-11 CN claimed
US-20230223869-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2023-07-13 US claimed
US-11601069-B2 Electrostatic machines that include a malonate in a dielectric fluid C-Motive Technologies, Inc. (US) 2023-03-07 US claimed
US-20220185817-A1 IRAK4 INHIBITORS ASTRAZENECA AB (SE) 2022-06-16 US claimed
WO-2022122876-A1 N-(IMIDAZO[1,2-B]PYRIDAZIN-3-YL)-1-CYCLOHEXYL-2H-INDAZOLE-5-CARBOXAMIDE AND N-(PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-1-CYCLOHEXYL-2H-INDAZOLE-5-CARBOXAMIDE DERIVATIVES AS IRAK4 INHIBITORS FOR THE TREATMENT OF ASTHMA ASTRAZENECA AB (SE) 2022-06-16 WO claimed
US-20210391809-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION NATIONAL SCIENCE FOUNDATION 2021-12-16 US claimed
US-20190296659-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-MOTIVE TECHNOLOGIES INC. (US) 2019-09-26 US claimed
US-9866148-B2 Electrostatic machine system and method of operation C-MOTIVE TECHNOLOGIES INC. (US) 2018-01-09 US claimed
EP-3205010-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies Inc. (US) 2017-08-16 EP claimed
US-20160099663-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION NATIONAL SCIENCE FOUNDATION 2016-04-07 US claimed
US-7186844-B2 Method for producing cyclic carbamate ester MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2007-03-06 US claimed
US-20050154200-A1 Method for producing cyclic carbamate ester MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-07-14 US claimed
US-6657015-B1 Method for the secondary cross-linking of hydrogels with 2-oxotetrahydro-1,3-oxazines BASF AKTIENGESELLSCHAFT (DE) 2003-12-02 US claimed
EP-0632022-B1 Process for the preparation of amino-substituted thioethers BAYER AG (DE) 1996-12-27 EP claimed
US-5410081-A Process for the preparation of amino-substituted thioethers BAYER AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
EP-0632022-A2 Process for the preparation of amino-substituted thioethers BAYER AG (DE) 1995-01-04 EP claimed