Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylstilbestrol Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.87 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylstilbestrol Diphosphate SCHEMBL6231203 | 0.93 | BLM (1.00) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| Diethylstilbestrol Diphosphate SCHEMBL9370 | 0.93 | BLM (1.00) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| Diethylstilbestrol Diphosphate SCHEMBL2496868 | 0.91 | BLM (0.96) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| Diethylstilbestrol Diphosphate SCHEMBL809597 | 0.91 | BLM (0.96) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| Diethylstilbestrol Diphosphate SCHEMBL3664191 | 0.90 | BLM (0.93) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| Diethylstilbestrol Diphosphate SCHEMBL5561062 | 0.89 | BLM (0.68) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| SCHEMBL707841 | 0.87 | BLM (0.87) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| SCHEMBL707840 | 0.87 | BLM (0.87) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| SCHEMBL14608595 | 0.84 | BLM (0.81) | BLMNR1I2SMN1; SMN2ESR1RECQL | |
| SCHEMBL554921 | 0.84 | NR1I2 (1.00) | BLMNR1I2SMN1; SMN2ESR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235561-A2 | FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE | Panacea Biotec Limited (IN) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001039749-A2 | FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE | PANACEA BIOTEC LIMITED (IN) | 2001-06-07 | — | — | WO | disclosed |