SCHEMBL7617847

SCHEMBL7617847

CC(=O)O[C@@H](OP(=O)(CC(Cc1ccc(-c2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MME P08473 7/20 0.51
ANPEP P15144 2/20 0.51
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
ECE1 P42892 1/20 0.41
ACE P12821 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617843 1.00 MME (0.51) MMEANPEPCTSSCTSKECE1
SCHEMBL7617852 1.00 MME (0.51) MMEANPEPCTSSCTSKECE1
SCHEMBL7615206 0.91 MME (0.51) MMEANPEPCTSSCTSKECE1
SCHEMBL7719784 0.91 MME (0.51) MMEANPEPCTSSCTSKECE1
SCHEMBL7722710 0.91 MME (0.51) MMEANPEPCTSSCTSKECE1
SCHEMBL7623827 0.85 MME (0.67) MMEANPEP
SCHEMBL7647059 0.85 MME (0.67) MMEANPEP
SCHEMBL7619534 0.84 MME (0.66) MMEANPEP
SCHEMBL7619545 0.84 MME (0.66) MMEANPEP
SCHEMBL7619529 0.84 MME (0.66) MMEANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1073664-B1 (ALPHA-AMINOPHOSPHINO) PEPTIDESDERIVATIVE AND COMPOSITIONS CONTAINING SAME INST NAT SANTE RECH MED (FR) 2002-10-23 EP disclosed