Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 19/20 | 0.84 |
| ▸ | SELE | P16581 | 19/20 | 0.84 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.83 |
| ▸ | CCNC | P24863 | 5/20 | 0.73 |
| ▸ | CDK8 | P49336 | 5/20 | 0.73 |
| ▸ | CDC7 | O00311 | 1/20 | 0.70 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.70 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.70 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | CDK1 | P06493 | 1/20 | 0.70 |
| ▸ | PIM1 | P11309 | 1/20 | 0.70 |
| ▸ | PRKACA | P17612 | 1/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | FLT4 | P35916 | 1/20 | 0.70 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.70 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.70 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051885 | 0.92 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7058854 | 0.91 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7054424 | 0.87 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7056270 | 0.87 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7054404 | 0.85 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7056782 | 0.85 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL5550362 | 0.83 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7055220 | 0.83 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL5550632 | 0.82 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7053795 | 0.82 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | claimed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | claimed |
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |