Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 17/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 17/20 | 0.62 |
| ▸ | ITGAL | P20701 | 17/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195786 | 1.00 | ITGB2 (0.62) | ITGB2ICAM1ITGALMAOB | |
| SCHEMBL6194902 | 0.98 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL27490241 | 0.88 | MAOB (0.54) | ITGB2ICAM1ITGALMAOB | |
| SCHEMBL27492373 | 0.86 | MAOB (0.51) | ITGB2ICAM1ITGALMAOB | |
| SCHEMBL27474403 | 0.84 | MAOB (0.47) | ITGB2ICAM1ITGALMAOB | |
| SCHEMBL5829912 | 0.84 | ITGB2 (0.48) | ITGB2ICAM1ITGALMAOB | |
| SCHEMBL6195780 | 0.79 | ITGB2 (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6197108 | 0.78 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL6194900 | 0.77 | ITGB2 (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6198485 | 0.77 | ITGAL (1.00) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |