Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.52 |
| ▸ | HSD17B7 | P56937 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618759 | 1.00 | SRD5A1 (0.52) | SRD5A1HSD17B7SRD5A2 | |
| SCHEMBL8927230 | 0.85 | SRD5A2 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL7621223 | 0.82 | SRD5A1 (0.52) | SRD5A1HSD17B7SRD5A2 | |
| SCHEMBL7621230 | 0.82 | SRD5A1 (0.52) | SRD5A1HSD17B7SRD5A2 | |
| SCHEMBL8926998 | 0.78 | SRD5A1 (0.60) | SRD5A1HSD17B7SRD5A2 | |
| SCHEMBL7614234 | 0.78 | SRD5A1 (0.59) | SRD5A1SRD5A2 | |
| SCHEMBL7616831 | 0.78 | SRD5A1 (0.59) | SRD5A1SRD5A2 | |
| SCHEMBL7614228 | 0.78 | SRD5A1 (0.59) | SRD5A1SRD5A2 | |
| SCHEMBL7713354 | 0.76 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL7713357 | 0.76 | SRD5A1 (0.51) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880540-B1 | 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE | AVENTIS PHARMA INC (US) | 2002-06-12 | — | — | EP | disclosed |