Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | NT5E | P21589 | 4/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619822 | 1.00 | POLB (0.57) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7621668 | 1.00 | POLB (0.57) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7622803 | 1.00 | POLB (0.57) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7621697 | 1.00 | POLB (0.57) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7892380 | 0.86 | CDK1 (0.47) | POLBNT5E | |
| SCHEMBL7897850 | 0.86 | CDK1 (0.47) | POLBNT5E | |
| SCHEMBL7898316 | 0.86 | CDK1 (0.47) | POLBNT5E | |
| SCHEMBL7891847 | 0.86 | CDK1 (0.47) | POLBNT5E | |
| SCHEMBL7903265 | 0.85 | HDAC6 (0.45) | NT5E | |
| SCHEMBL7898263 | 0.85 | HDAC6 (0.45) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444656-B1 | (5R)-(2-AMINO-6-HYDROXY-PURIN-9-YLMETHYL)-(4R)-AZIDO-TETRAHYDR O-FURAN-(2S)- PHOSPHONATE; PARTICULARLY AGAINST HIV AND/OR HBV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-09-03 | — | — | US | disclosed |