⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619936 | 1.00 | — | — | |
| SCHEMBL27851785 | 0.97 | — | — | |
| SCHEMBL12491703 | 0.74 | — | — | |
| SCHEMBL11692067 | 0.74 | — | — | |
| SCHEMBL1070780 | 0.74 | — | — | |
| SCHEMBL9186924 | 0.72 | — | — | |
| SCHEMBL27453694 | 0.72 | — | — | |
| SCHEMBL3155592 | 0.72 | — | — | |
| SCHEMBL28776124 | 0.72 | — | — | |
| SCHEMBL8226636 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | claimed |
| EP-0454511-B1 | N-substituted heterocycle derivatives, their preparation, compositions containing them | SANOFI SA (FR) | 1998-06-17 | — | — | EP | claimed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | claimed |
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | claimed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | claimed |
| EP-0888325-B1 | NOVEL CYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6114390-A | AN ARGININAMIDE OR ORNITHINAMIDE COMPOUND AS TREATING MEMORY LOSS, MIGRAINE, SLEEP DISORDERS, PAIN, CARDIOVASCULAR DISEASES, SUBARACHNOIDAL BLEEDING, VASCULAR-HYPERTROPHIC CHANGES, CEREBRAL AND CORONARY VASOSPASMS | KARL THOMAE GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5929088-A | TREATMENT OF EPILEPSY, FAINTING, NEURODEGENERATIVE DISORDERS, ANXIETY, PAIN, PANIC ATTACKS | WARNER-LAMBERT COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0888325-A1 | NOVEL CYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997029101-A1 | NOVEL CYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-08-14 | — | — | WO | disclosed |
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5543528-A | Imidazolines | SANOFI (FR) | 1996-08-06 | — | — | US | disclosed |
| US-5434167-A | Angiotensin II antagonists | SANOFI (FR) | 1995-07-18 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |
| EP-0562936-A1 | Imidazolines N-substituted by a biphenylmethyl group, their preparation, the pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-29 | — | — | EP | disclosed |
| EP-0532410-A1 | N-substituted heterocyclic derivatives as angiotensin II inhibitors | SANOFI (FR) | 1993-03-17 | — | — | EP | disclosed |