Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 9/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.42 |
| ▸ | GPR183 | P32249 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220976 | 0.91 | GPR183 (0.38) | ITGALITGB2ICAM1GPR183KDM4E | |
| SCHEMBL6222372 | 0.89 | PARP14 (0.38) | ITGALITGB2ICAM1GPR183KDM4E | |
| SCHEMBL6219495 | 0.88 | GPR183 (0.37) | ITGALITGB2ICAM1GPR183KDM4E | |
| SCHEMBL6219884 | 0.87 | ITGAL (0.40) | ITGALITGB2ICAM1GPR183KDM4E | |
| SCHEMBL6199876 | 0.84 | ITGAL (0.55) | ITGALITGB2ICAM1 | |
| SCHEMBL6218188 | 0.82 | ITGAL (0.39) | ITGALITGB2ICAM1GPR183KDM4E | |
| SCHEMBL6221367 | 0.82 | ITGB2 (0.52) | ITGALITGB2ICAM1KDM4EALDH1A1 | |
| SCHEMBL6220050 | 0.81 | ITGAL (0.39) | ITGALITGB2ICAM1GPR183RAB9A | |
| SCHEMBL6199888 | 0.80 | ITGAL (0.41) | ITGALITGB2ICAM1ENPP2ALDH1A1 | |
| SCHEMBL6220749 | 0.80 | HTT (0.51) | KDM4EENPP2ALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | claimed |
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | disclosed |