SCHEMBL7620754

SCHEMBL7620754

[O-2].[O-2].[O-2].[Ti+6]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11311069 0.82
SCHEMBL11220859 0.82
SCHEMBL29389890 0.71
SCHEMBL29512245 0.71
SCHEMBL29377526 0.71
Methane SCHEMBL28750057 0.71
SCHEMBL29715907 0.71
SCHEMBL30905106 0.71
SCHEMBL21418 0.71
SCHEMBL2266230 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423967-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS ARES TRADING S.A. (CH) 2024-12-26 US disclosed
US-12083107-B2 Pharmaceutical compositions comprising glitazones and Nrf2 activators Kahrs, Bjoern Colin (CH) 2024-09-10 US disclosed
EP-2793876-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS KAHRS BJOERN COLIN (CH) 2023-10-04 EP disclosed
US-20230190720-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS KAHRS, Bjoern Colin (CH) 2023-06-22 US disclosed
US-11484530-B2 Pharmaceutical compositions comprising the PPAR agonist INT-131 and Nrf2 activators Kahrs, Bjoern Colin (CH) 2022-11-01 US disclosed
US-20220166014-A1 SURFACE TREATMENT SOLUTION, METHOD FOR PREPARING SURFACE TREATMENT SOLUTION, METHOD FOR PREPARING ACTIVE MATERIAL USING SURFACE TREATMENT SOLUTION, AND ACTIVE MATERIAL PREPARED THEREBY HYUNDAI MOTOR COMPANY (KR) 2022-05-26 US disclosed
US-10426763-B2 Pharmaceutical compositions comprising glitazones and NRF2 activators Kahrs, Bjoern Colin (CH) 2019-10-01 US disclosed
US-20170065571-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS ARES TRADING S.A. (CH) 2017-03-09 US disclosed
CN-106457237-A Methods for reprocessing used catalysts 托品能企业有限公司 2017-02-22 CN disclosed
US-9504679-B2 Pharmaceutical compositions comprising glitazones and Nrf2 activators Kahrs, Bjoern Colin (CH) 2016-11-29 US disclosed
WO-2016074684-A1 FUMARIC ACID DERIVATIVES FOR MEDICAL USE SYDDANSK UNIVERSITET (DK) 2016-05-19 WO disclosed
US-8524773-B2 Utilization of dialkylfumarates BIOGEN IDEC INTERNATIONAL GMBH (CH) 2013-09-03 US disclosed
US-20130004526-A1 Utilization of Dialkylfumarates BIOGEN IDEC INTERNATIONAL GMBH (CH) 2013-01-03 US disclosed
US-6436992-B1 ADMINISTERING MONO/DIALKYL ESTER METAL SALTS, FOR PROPHYLAXIS OF AUTOIMMUNE DISEASES, SELECTED FROM GRAFT-VERSUS HOST/GRAVE'S DISEASE, DIABETES, THYROIDS, SJOGREN'S SYNDROME, PERNICIOUS ANAEMIA, MULTIPLE SCLEROSIS OR HEPATITIS FUMAPHARM AG (CH) 2002-08-20 US disclosed
US-5424332-A For treating psoriasis and psoriatic arthritis; using fumaric acid monoalkylester calcium, iron or magnesium salt SPEISER PETER P (CH) 1995-06-13 US disclosed
US-4959389-A MONOALKYL FUMARATE SALTS, DIALKYL FUMARATES SPEISER PETER P (CH) 1990-09-25 US disclosed