SCHEMBL7621

SCHEMBL7621

O=C(CBr)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 11/20 1.00
PTPN1 P18031 7/20 1.00
MAPK1 P28482 2/20 0.64
MAPT P10636 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
CYP3A4 P08684 1/20 0.64
HPGD P15428 1/20 0.64
ALOX15 P16050 1/20 0.64
CES1 P23141 1/20 0.64
KMT2A Q03164 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
TRPA1 O75762 1/20 0.58
ALDH1A1 P00352 1/20 0.58
HIF1A Q16665 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 1/20 0.56
NR4A2 P43354 1/20 0.56
ERCC5 P28715 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19331717 1.00 GSK3B (1.00) GSK3BPTPN1MAPK1MAPTTDP1
SCHEMBL18849535 1.00 GSK3B (1.00) GSK3BPTPN1MAPK1MAPTTDP1
Hydrochloric Acid SCHEMBL28021184 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Hydrogen Sulfide SCHEMBL7496567 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Fluoride SCHEMBL27997580 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Bromide SCHEMBL28774450 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
SCHEMBL27822538 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Methane SCHEMBL7161301 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Water SCHEMBL28144749 0.97 GSK3B (0.95) GSK3BPTPN1MAPK1MAPTTDP1
Ethylene SCHEMBL11829369 0.95 GSK3B (0.91) GSK3BPTPN1MAPK1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13419 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079820-A Synthesis method of aromatic formate compound 2026-05-26 CN claimed
CN-119176805-B Coumarin selenoether thiazole hydrazone derivative and preparation method and application thereof 宜春学院 2025-06-10 CN claimed
CN-119930229-A High-strength anti-cracking concrete material and preparation method thereof 佛山市顺德区有利建筑构件有限公司 2025-05-06 CN claimed
CN-119930622-A Antitumor matrine hydrazine thiazole derivative and preparation method and application thereof 南京林业大学 2025-05-06 CN claimed
CN-115595147-B Light capturing system based on continuous energy transfer of column arene and preparation method and application thereof 常州大学 2025-05-06 CN claimed
CN-119930621-A Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof 南京林业大学 2025-05-06 CN claimed
CN-116262673-B Preparation method of alpha-bromoacetophenone compound 浙江工业大学 2025-04-29 CN claimed
CN-119661534-A Matrine aminothiazole derivative and preparation method and application thereof 南京林业大学 2025-03-21 CN claimed
CN-119534681-A Method for measuring dextromethorphan in levocarnitine product by utilizing high performance liquid chromatography 深圳海王医药科技研究院有限公司 2025-02-28 CN claimed
CN-114685607-B Preparation method of eptifibatide impurity I 深圳翰宇药业股份有限公司 2025-02-28 CN claimed
US-4048036-A CURING, PHOTOINITIATOR PPG INDUSTRIES, INC. (US) 1977-09-13 US claimed
US-4028264-A Polybutene composition containing halo-carbonyl additives and use thereof STANDARD OIL COMPANY (INDIANA) (US) 1977-06-07 US claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed
US-4025695-A LAMINATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-05-24 US claimed
US-3985832-A BY REACTING CHLORINATED RUBBER WITH A BROMINE OR IODINE COMPOUND EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-10-12 US claimed
US-3982942-A MANGANESE CARBONYL CATALYST ICI UNITED STATES INC. (US) 1976-09-28 US claimed
US-3979482-A HALOGENATED CARBONYL COMPOUNDS, ULTRAVIOLET RADIATION Kagiya, Tsutomu (JA) 1976-09-07 US claimed
US-3954584-A Photopolymerizable vinylurethane liquid composition KANSAI PAINT COMPANY (JA) 1976-05-04 US claimed
US-3953475-A MALEIC ANHYDRIDE STANDARD OIL COMPANY (US) 1976-04-27 US claimed
US-3932356-A UNSATURATED POLYETHERESTER CONTAINING GLYCIDYL (METH)ACRYLATE OR ALLYL GLYCIDYL ETHER RESIDUES KANSAI PAINT COMPANY, LTD. (JA) 1976-01-13 US claimed