Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.79 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.79 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830363 | 1.00 | ITGAL (0.79) | ITGALITGB2ICAM1MAPTHTT | |
| SCHEMBL27474895 | 0.92 | ITGAL (0.67) | ITGALITGB2ICAM1 | |
| SCHEMBL5830203 | 0.90 | ITGAL (0.72) | ITGALITGB2ICAM1MAPTHTT | |
| SCHEMBL7619100 | 0.90 | ITGAL (0.72) | ITGALITGB2ICAM1MAPTHTT | |
| SCHEMBL5829931 | 0.88 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5830196 | 0.86 | ITGAL (0.82) | ITGALITGB2ICAM1 | |
| SCHEMBL8091330 | 0.85 | ITGAL (0.81) | ITGALITGB2ICAM1 | |
| SCHEMBL7619718 | 0.85 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5830397 | 0.85 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL6199578 | 0.84 | ITGAL (0.75) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |