Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 5/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621351 | 0.90 | P2RY12 (0.48) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL8972151 | 0.90 | P2RY12 (0.48) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL8584884 | 0.90 | P2RY12 (0.48) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL26068423 | 0.88 | POLB (0.56) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL22327447 | 0.88 | POLB (0.56) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL30473748 | 0.88 | POLB (0.56) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL7623380 | 0.88 | POLB (0.56) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL7620290 | 0.86 | ADORA1 (0.47) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL7625440 | 0.83 | ADORA1 (0.43) | ADORA1POLBENPP1P2RY1AHCY | |
| SCHEMBL10436009 | 0.81 | BCHE (0.52) | ADORA1AHCYNT5ETP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444798-B1 | GENETIC ENGINEERING | BENNER, STEVEN | 2002-09-03 | — | — | US | disclosed |