Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.73 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.73 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.73 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.73 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.55 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514080 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3509655 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL7615633 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL1554624 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL296505 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL23674394 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL30096682 | 1.00 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| Hydrochloric Acid SCHEMBL7614632 | 0.99 | S1PR1 (0.71) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| Water SCHEMBL7896708 | 0.99 | S1PR1 (0.71) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL4822056 | 0.99 | S1PR1 (0.70) | S1PR1S1PR4S1PR3S1PR5TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | claimed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | claimed |
| US-6372800-B1 | IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |