⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120860 | 0.93 | — | — | |
| SCHEMBL28652168 | 0.76 | — | — | |
| SCHEMBL20504145 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL9523237 | 0.69 | — | — | |
| SCHEMBL9490210 | 0.67 | GAA (0.31) | — | |
| SCHEMBL11112738 | 0.67 | — | — | |
| SCHEMBL9517757 | 0.65 | — | — | |
| SCHEMBL5133525 | 0.65 | — | — | |
| SCHEMBL10534107 | 0.64 | — | — | |
| SCHEMBL15541926 | 0.62 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856740-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020063870-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-04-02 | — | — | WO | disclosed |
| US-6458826-B2 | A PYRROLIDINE COMPOUND USED AS REPELLANT FOR PESTS, INSECTS, MITES AND TICKS ON ANIMALS AND HUMAN | NAVARTIS ANIMAL HEALTH US, INC. | 2002-10-01 | — | — | US | disclosed |
| EP-1087660-B1 | COMPOSITION FOR KEEPING AWAY VERMIN | NOVARTIS AG (CH) | 2002-08-07 | — | — | EP | disclosed |
| US-20010002402-A1 | A pyrrolidine compound used as repellant for pests, insects, mites and ticks on animals and human | NOVARTIS ANIMAL HEALTH US, INC. | 2001-05-31 | — | — | US | disclosed |
| EP-1087660-A1 | COMPOSITION FOR KEEPING AWAY VERMIN | Novartis AG (Novartis SA) (Novartis Inc.) (CH) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065308-A1 | COMPOSITION FOR KEEPING AWAY VERMIN | NOVARTIS AG (CH) | 1999-12-23 | — | — | WO | disclosed |
| EP-0128120-A2 | Trisubstituted oxazolidinones | CIBA-GEIGY AG (CH) | 1984-12-12 | — | — | EP | disclosed |