SCHEMBL7621678

SCHEMBL7621678

CCN1C(=O)N(CC)C(Br)(Br)C1=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.44
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
CTRC Q99895 1/20 0.44
GMNN O75496 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
THPO P40225 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MGLL Q99685 1/20 0.34
CHRM2 P08172 1/20 0.31
CHRM3 P20309 1/20 0.31
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696234 0.76 F2 (0.46) F2ELANECTSGCTRCGMNN
SCHEMBL13853161 0.74 F2 (0.44) F2ELANECTSGCTRCGMNN
SCHEMBL8582589 0.74 F2 (0.44) F2ELANECTSGCTRCGMNN
SCHEMBL13853164 0.72 F2 (0.42) F2ELANECTSGCTRCGMNN
SCHEMBL1361995 0.72 F2 (0.42) F2ELANECTSGCTRCGMNN
SCHEMBL5704499 0.71 F2 (0.41) F2ELANECTSGCTRCGMNN
SCHEMBL28772946 0.71 F2 (0.41) F2ELANECTSGCTRCGMNN
SCHEMBL1362206 0.69 F2 (0.39) F2ELANECTSGCTRCGMNN
SCHEMBL19923745 0.66 BACE1 (0.46) ELANELMNAMAPTNPSR1
SCHEMBL6086218 0.66 F2 (0.35) F2ELANECTSGCTRCCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264046-A2 PARTIALLY HALOGENATED HYDANTOINS IN SLIME CONTROL LONZA INC. (US) 2002-12-11 EP disclosed
US-6429181-B2 ADDING PARTIALLY HALOGENATED HYDANTOIN TO THE SLURRY IN A PREFERED CONCENTRATION FOR REDUCING SLIME IN CIRCULATING WATER SLURRY, CONTAINING PERFORMANCE ADDITIVES AND ORGANIC MATTERS WITHOUT DECOMPOSING THE ADDITIVES LONZA INC. 2002-08-06 US disclosed
US-20020003114-A1 Partially halogenated hydantoins in papermaking applications LONZA INC.; 2002-01-10 US disclosed
WO-2001055036-A2 PARTIALLY HALOGENATED HYDANTOINS IN SLIME CONTROL LONZA INC. (US) 2001-08-02 WO disclosed