Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762708 | 0.98 | NPC1 (0.42) | NPC1NAAA | |
| SCHEMBL4516905 | 0.98 | NPC1 (0.47) | NPC1NAAA | |
| SCHEMBL4326261 | 0.96 | NPC1 (0.43) | NPC1NAAA | |
| SCHEMBL20371021 | 0.92 | NPC1 (0.42) | NPC1NAAA | |
| SCHEMBL4798852 | 0.89 | SPHK1 (0.32) | NPC1 | |
| SCHEMBL9011682 | 0.89 | NPC1 (0.54) | NPC1NAAA | |
| SCHEMBL262805 | 0.89 | NPC1 (0.54) | NPC1NAAA | |
| SCHEMBL9011791 | 0.89 | NPC1 (0.54) | NPC1NAAA | |
| SCHEMBL9011906 | 0.89 | NPC1 (0.54) | NPC1NAAA | |
| SCHEMBL9011558 | 0.86 | NPC1 (0.56) | NPC1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |