SCHEMBL7621733

SCHEMBL7621733

FC1Cc2ccccc2C(F)C1F

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.45
MAOA P21397 2/20 0.45
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
KDM1A O60341 4/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA4 P43681 2/20 0.38
HTR2A P28223 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16242534 0.86 MAOB (0.47) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL2821725 0.74 KDM1A (0.47) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL2824969 0.74 KDM1A (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2824963 0.74 KDM1A (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL23383992 0.74 MAOB (0.49) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL23490000 0.74 MAOB (0.45) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL30715525 0.74 MAOB (0.45) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL14870555 0.74 MAOB (0.49) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL8782162 0.74 MAOB (0.45) MAOBMAOAGRIN2DGRIN3BGRIN1
SCHEMBL2821728 0.74 KDM1A (0.47) MAOBMAOAGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002284722-A METHOD FOR PRODUCING 5,6,7-TRIFLUORO-1,2,3,4- TETRAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK & CHEM INC 2002-10-03 JP disclosed