Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617307 | 0.99 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7615879 | 0.94 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7619502 | 0.93 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7621717 | 0.93 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7614857 | 0.92 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7714184 | 0.90 | FFAR1 (0.53) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL7615830 | 0.89 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7614731 | 0.89 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7619648 | 0.89 | S1PR1 (0.53) | S1PR1S1PR4S1PR3S1PR5RARB | |
| SCHEMBL7619345 | 0.89 | S1PR1 (0.53) | S1PR1S1PR4S1PR3S1PR5RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372800-B1 | IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |