Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.67 |
| ▸ | FASN | P49327 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | TERT | O14746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20942832 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL9751131 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL23698116 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL23698114 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL16431297 | 0.96 | PTPN1 (0.68) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL8755527 | 0.96 | PTPN1 (0.62) | PTPN1FASNKDM4EPPARGPPARA | |
| SCHEMBL28188702 | 0.96 | PTPN1 (0.71) | PTPN1FASNPPARGPPARAFAAH | |
| SCHEMBL17867131 | 0.96 | PTPN1 (0.71) | PTPN1FASNPPARGPPARAFAAH | |
| SCHEMBL17867134 | 0.96 | PTPN1 (0.71) | PTPN1FASNPPARGPPARAFAAH | |
| SCHEMBL23116359 | 0.94 | PTPN1 (0.68) | PTPN1FASNPPARGPPARAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227809-A2 | HETEROATOM-INTERRUPTED ANALOGS OF 15-HYDROXYEICOSATETRAENOIC ACID AND METHODS OF USE | Alcon Universal, Ltd. (CH) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034129-A2 | HETEROATOM-INTERRUPTED ANALOGS OF 15-HYDROXYEICOSATETRAENOIC ACID AND METHODS OF USE | ALCON UNIVERSAL LTD. (CH) | 2001-05-17 | — | — | WO | disclosed |