Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648817 | 0.80 | HSD17B10 (0.35) | ALDH1A1 | |
| SCHEMBL8564324 | 0.80 | HTT (0.44) | HTTADORA3ADORA1EGLN1ALDH1A1 | |
| SCHEMBL7617376 | 0.72 | HTT (0.30) | HTT | |
| SCHEMBL6032862 | 0.69 | PDE3B (0.30) | — | |
| SCHEMBL558087 | 0.68 | MGAM (0.39) | — | |
| SCHEMBL18894088 | 0.67 | NOTUM (0.31) | — | |
| SCHEMBL18894149 | 0.67 | GRIN2D (0.32) | — | |
| SCHEMBL13898339 | 0.67 | MEN1 (0.44) | HTTADORA3ADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29804799 | 0.67 | MEN1 (0.44) | HTTADORA3ADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14468054 | 0.67 | HTT (0.39) | HTTADORA3ADORA1EGLN1PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |