SCHEMBL7623360

SCHEMBL7623360

O=C(CCCCS)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.58
PRSS2 P07478 1/20 0.58
PRSS3 P35030 1/20 0.58
KMT2A Q03164 5/20 0.51
HDAC3 O15379 9/20 0.51
HDAC1 Q13547 9/20 0.51
HDAC2 Q92769 9/20 0.51
HDAC10 Q969S8 9/20 0.51
HDAC11 Q96DB2 9/20 0.51
HDAC8 Q9BY41 9/20 0.51
HDAC6 Q9UBN7 9/20 0.51
HDAC4 P56524 8/20 0.51
HDAC7 Q8WUI4 8/20 0.51
HDAC9 Q9UKV0 8/20 0.51
HDAC5 Q9UQL6 8/20 0.51
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
CYP19A1 P11511 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7631432 0.94 PRSS1 (0.55) PRSS1PRSS2PRSS3KMT2AHDAC3
SCHEMBL43233 0.90 PRSS1 (0.67) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL5161147 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL43568 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL3165609 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL25297232 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL1531270 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL20564639 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL21879662 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1
SCHEMBL3680357 0.88 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850987-B1 Improved PVC foam compositions MORTON INT INC (US) 2002-03-27 EP disclosed
US-5786399-A PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-28 US disclosed
EP-0850987-A1 Improved PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-01 EP disclosed
US-5753719-A ACTIVATOR FOR BLOWING AGENTS MORTON INTERNATIONAL, INC. (US) 1998-05-19 US disclosed
US-5726213-A FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT MORTON INTERNATIONAL, INC. (US) 1998-03-10 US disclosed
EP-0254392-A2 Stabilizers for halogen-containing polymers MORTON INTERNATIONAL, INC. (US) 1988-01-27 EP disclosed
US-4711920-A HEAT AND RADIATION RESISTANCE; WEATHERPROOFING; NONIRRITATING TO EYES AND MUCUS MEMBRANES MORTON THIOKOL, INC. (US) 1987-12-08 US disclosed
EP-0051284-B1 NOVEL THIAPROSTAGLANDIN E1 DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS TEIJIN LIMITED (JP) 1985-01-09 EP disclosed
US-4466980-A Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1984-08-21 US disclosed
EP-0051284-A1 Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds TEIJIN LIMITED (JP) 1982-05-12 EP disclosed
US-RE30810-E HEAT STABILIZERS FOR POLYMERS THIOKOL CORPORATION (US) 1981-12-01 US disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE30032-E POLYMER STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-06-12 US disclosed
US-4120845-A FOR VINYL OR VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1978-10-17 US disclosed
US-4062881-A POLYVINYL CHLORIDE CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-12-13 US disclosed
US-3979359-A STABILIZERS FOR VINYL- AND VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-09-07 US disclosed