Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057736 | 0.85 | LCK (0.74) | LCK | |
| SCHEMBL6057796 | 0.84 | LCK (0.78) | LCK | |
| SCHEMBL6057811 | 0.84 | LCK (0.84) | LCK | |
| SCHEMBL6057730 | 0.84 | LCK (0.76) | LCK | |
| SCHEMBL6058027 | 0.83 | LCK (1.00) | LCK | |
| SCHEMBL6058139 | 0.83 | LCK (0.87) | LCK | |
| SCHEMBL6057875 | 0.82 | LCK (0.81) | LCK | |
| SCHEMBL6058019 | 0.82 | LCK (0.74) | LCK | |
| SCHEMBL6057633 | 0.81 | LCK (1.00) | LCK | |
| SCHEMBL6057845 | 0.81 | LCK (0.73) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037632-A4 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1037632-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999024035-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |