Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623948 | 1.00 | MAPT (0.48) | MAPTTDP1KMONPC1RAB9A | |
| SCHEMBL7635474 | 0.98 | MAPT (0.49) | MAPTTDP1KMONPC1RAB9A | |
| SCHEMBL7625023 | 0.86 | SLC6A2 (0.47) | MAPTNPC1RAB9AF2LMNA | |
| SCHEMBL7630420 | 0.86 | SLC6A2 (0.47) | MAPTNPC1RAB9AF2LMNA | |
| SCHEMBL7635512 | 0.86 | F2 (0.57) | MAPTTDP1F2LMNASLC6A2 | |
| SCHEMBL7629416 | 0.86 | F2 (0.57) | MAPTTDP1F2LMNASLC6A2 | |
| SCHEMBL7629907 | 0.84 | PDCD1 (0.47) | MAPTNPC1RAB9AF2LMNA | |
| SCHEMBL7632142 | 0.84 | F2 (0.59) | MAPTTDP1F2LMNASLC6A2 | |
| SCHEMBL7631816 | 0.81 | KMT2A (0.49) | MAPTNPC1RAB9AHDAC8SLC6A2 | |
| SCHEMBL7628543 | 0.81 | KMT2A (0.49) | MAPTNPC1RAB9AHDAC8SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |