Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625486 | 1.00 | SLC2A1 (0.48) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7607741 | 0.86 | SLC2A1 (0.51) | SLC2A1MCHR1MAPTMEN1KMT2A | |
| SCHEMBL7607738 | 0.86 | SLC2A1 (0.51) | SLC2A1MCHR1MAPTMEN1KMT2A | |
| SCHEMBL7614369 | 0.86 | SLC2A1 (0.53) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7614377 | 0.86 | SLC2A1 (0.53) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7618392 | 0.85 | SLC2A1 (0.64) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7618386 | 0.85 | SLC2A1 (0.64) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7616765 | 0.85 | SLC2A1 (0.55) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7616769 | 0.85 | SLC2A1 (0.55) | SLC2A1IMPDH2MCHR1MAPTMEN1 | |
| SCHEMBL7610671 | 0.84 | SLC2A1 (0.51) | SLC2A1IMPDH2MCHR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |