SCHEMBL7625549

SCHEMBL7625549

CCON=C(C)c1ccc(OCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)nc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.31
LSS P48449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615480 0.98 SMN1; SMN2 (0.34) SMN1; SMN2MAPTHTT
SCHEMBL7615472 0.98 SMN1; SMN2 (0.34) SMN1; SMN2MAPTHTT
SCHEMBL7623843 0.95 SMN1; SMN2 (0.35) SMN1; SMN2HTT
SCHEMBL7619887 0.94 SMN1; SMN2 (0.33) SMN1; SMN2HTT
SCHEMBL7625124 0.93 SMN1; SMN2 (0.35) SMN1; SMN2HTT
SCHEMBL7618654 0.92 SMN1; SMN2 (0.33) SMN1; SMN2HTT
SCHEMBL7622592 0.91 HTT (0.32) HTT
SCHEMBL7619271 0.89 MAPT (0.32) MAPTHTT
SCHEMBL7619169 0.89 HTT (0.30) HTT
SCHEMBL7615454 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed