Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.73 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286612 | 0.85 | PPARA (0.69) | PPARACYP4A11PPARGCYP4F2ABCB11 | |
| SCHEMBL3839840 | 0.84 | PPARA (1.00) | PPARAPPARGCYP1A2CYP3A4PPARD | |
| SCHEMBL5661528 | 0.84 | PPARA (0.59) | PPARACYP4A11PPARGCYP4F2LTA4H | |
| SCHEMBL14526638 | 0.84 | PPARA (0.59) | PPARACYP4A11PPARGCYP4F2LTA4H | |
| SCHEMBL30730123 | 0.84 | PPARA (0.70) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL4575624 | 0.83 | PPARA (0.53) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL13792687 | 0.82 | PPARA (0.65) | PPARACYP4A11PPARGCYP4F2ABCB11 | |
| SCHEMBL2982136 | 0.82 | CYP4A11 (0.54) | PPARACYP4A11CYP4F2LTA4HEPHX2 | |
| SCHEMBL10733316 | 0.82 | PPARA (0.53) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL3286903 | 0.81 | PPARA (0.63) | PPARACYP4A11PPARGCYP4F2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |