SCHEMBL7625677

SCHEMBL7625677

C=C[Si](C)(C)c1ccc(C(=O)OO[C]2CCC(C(C)(C)C)CC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 2/20 0.38
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635481 0.91 MEN1 (0.40) MEN1KMT2AMAPTKDM4ETP53
SCHEMBL7635346 0.87 NR1H2 (0.34) MAPTNR1H2NR1H3ALDH1A1SMN1; SMN2
SCHEMBL7630116 0.87 MEN1 (0.44) MEN1KMT2AMAPTKDM4ETP53
SCHEMBL7629450 0.85 MEN1 (0.38) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL7635321 0.85 MEN1 (0.38) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL7630995 0.84 NR1H2 (0.37) NR1H2NR1H3
SCHEMBL7635542 0.84 NR1H2 (0.32) NR1H2NR1H3
SCHEMBL7630072 0.83 NR1H2 (0.36) NR1H2NR1H3RAB9A
SCHEMBL7625551 0.83 NR1H2 (0.36) NR1H2NR1H3RAB9A
SCHEMBL7628498 0.82 CYP1A2 (0.33) KMT2AMAPTNR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed