Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071669 | 0.82 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL19371379 | 0.81 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14868311 | 0.79 | NPC1 (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL28480228 | 0.78 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL1937211 | 0.78 | NPC1 (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL28482365 | 0.78 | NPC1 (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL28482475 | 0.78 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL17186270 | 0.77 | NPC1 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7428059 | 0.76 | CA12 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Dichloroacetic Acid SCHEMBL11694917 | 0.73 | NPC1 (0.49) | CA12CA9NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108536-A | Biguanide compound and application thereof | 伊谬诺米特医疗有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-6488942-B1 | CHLOROPHENYL BIGUANIDE AND/OR CHLOROBENZYL BIGUANIDE COMPOUNDS AND BENZOIC ACID IN AN AQUEOUS ALCOHOLIC SOLUTION, USE IN THE DENTAL FIELD; CHLORHEXIDINE; STORAGE STABLE MOUTHWASH | DDG DENTAL DEVICES GMBH (DE) | 2002-12-03 | — | — | US | claimed |
| EP-1023036-B1 | DISINFECTING AGENT | DDG DENTAL DEVICES GMBH (DE) | 2002-01-09 | — | — | EP | claimed |
| EP-1023036-A2 | DISINFECTING AGENT | DDG Dental Devices GmbH (DE) | 2000-08-02 | — | — | EP | claimed |
| WO-1999020228-A2 | DISINFECTING AGENT | DDG DENTAL DEVICES GMBH (DE) | 1999-04-29 | — | — | WO | claimed |
| WO-2023115158-A1 | COATING COMPOSITIONS | Silfresh Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| CN-107108536-A | Biguanide compound and application thereof | 伊谬诺米特医疗有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2012119155-A1 | ANTIMICROBIAL COMPOSITIONS FOR TOOTH FLUORIDATION AND REMINERALIZATION | AMERICAN DENTAL ASSOCIATION FOUNDATION (US) | 2012-09-07 | — | — | WO | disclosed |
| US-6488942-B1 | CHLOROPHENYL BIGUANIDE AND/OR CHLOROBENZYL BIGUANIDE COMPOUNDS AND BENZOIC ACID IN AN AQUEOUS ALCOHOLIC SOLUTION, USE IN THE DENTAL FIELD; CHLORHEXIDINE; STORAGE STABLE MOUTHWASH | DDG DENTAL DEVICES GMBH (DE) | 2002-12-03 | — | — | US | disclosed |
| US-6488942-B1 | CHLOROPHENYL BIGUANIDE AND/OR CHLOROBENZYL BIGUANIDE COMPOUNDS AND BENZOIC ACID IN AN AQUEOUS ALCOHOLIC SOLUTION, USE IN THE DENTAL FIELD; CHLORHEXIDINE; STORAGE STABLE MOUTHWASH | DDG DENTAL DEVICES GMBH (DE) | 2002-12-03 | — | — | US | disclosed |
| EP-1023036-A2 | DISINFECTING AGENT | DDG Dental Devices GmbH (DE) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020228-A2 | DISINFECTING AGENT | DDG DENTAL DEVICES GMBH (DE) | 1999-04-29 | — | — | WO | disclosed |
| WO-1998004143-A2 | A PROCESS FOR THE DECONTAMINATION OF MEATS | THE DOW CHEMICAL COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |
| EP-0074082-B1 | STABLE ORAL COMPOSITIONS CONTAINING ZINC AND FLUORIDE COMPOUNDS | Richardson-Vicks, Inc. (US) | 1987-10-21 | — | — | EP | disclosed |