Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622471 | 0.95 | TDP1 (0.38) | CES2ACHECES1MAPTSMN1; SMN2 | |
| SCHEMBL3367989 | 0.90 | PPARA (0.42) | MAPTSMN1; SMN2TDP1HTTNPC1 | |
| SCHEMBL7627025 | 0.90 | PPARA (0.41) | CES2ACHECES1MAPTSMN1; SMN2 | |
| SCHEMBL7627033 | 0.85 | TDP1 (0.40) | CES2ACHECES1MAPTSMN1; SMN2 | |
| SCHEMBL3372532 | 0.85 | PPARA (0.44) | MAPTSMN1; SMN2TDP1HTTNPC1 | |
| SCHEMBL7629752 | 0.85 | POLB (0.45) | MAPTSMN1; SMN2TDP1HTTNPC1 | |
| SCHEMBL7631080 | 0.85 | PPARA (0.41) | TDP1HTTGAAPOLBAPEX1 | |
| SCHEMBL7629965 | 0.83 | CYP1A2 (0.40) | MEN1KMT2AMAPK1TDP1HTT | |
| SCHEMBL7626513 | 0.83 | POLB (0.35) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7627000 | 0.82 | HTT (0.33) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237963-A1 | ARTICLES FORMED FROM PROPYLENE DIENE COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042323-A1 | ARTICLES FORMED FROM PROPYLENE DIENE COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| US-6242551-B1 | SUCH AS CONTACT LENSES, INTRAOCULAR LENSES, AND ARTIFICIAL CORNEA; REDUCES SEPARATION OR ELUTION, CHEMICALLY STABLE, AND DOES NOT DENATURE UNDER HYDROLYSIS; MAINTAINS ORIGINAL COLOR TONE | MENICON CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |