Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7631936 | 1.00 | NPC1 (0.42) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| Iodide SCHEMBL7626482 | 1.00 | NPC1 (0.42) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL30645316 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL29048074 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL1832602 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL6296126 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL20787057 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL1831748 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL1835103 | 0.98 | NPC1 (0.43) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL7626321 | 0.96 | NPC1 (0.42) | NPC1RAB9AHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769517-B1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN IND LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5684065-A | LASER BEAM | DAIKIN INDUSTRIES, LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0769517-A1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |