Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631080 | 0.95 | PPARA (0.41) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL3372532 | 0.91 | PPARA (0.44) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7627033 | 0.91 | TDP1 (0.40) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7629752 | 0.89 | POLB (0.45) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7626546 | 0.87 | POLB (0.39) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL3367989 | 0.86 | PPARA (0.42) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7627025 | 0.86 | PPARA (0.41) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7622471 | 0.86 | TDP1 (0.38) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7626513 | 0.82 | POLB (0.35) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7628769 | 0.82 | CYP1A2 (0.39) | POLBAPEX1HTTTDP1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030194-B1 | Material for a soft intraocular lens | MENICON CO LTD (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6326448-B1 | HYDROPHILIC MONOMER; LENSES | MENICON CO., LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| US-6320008-B2 | COPOLYMER OF A (METH)ACRYLOYLOXYALKOXY-, VINYLPHENYLALKYLOXY-, OR VINYLPHENOXYALKOXY-SUBSTITUTED ARYLENEAZOARENE COMPOUND. | MENICON CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| US-20010021759-A1 | Polymeric colorant and colored material for ocular lens using the colorant | MENICON CO., LTD. | 2001-09-13 | — | — | US | disclosed |
| US-6277940-B1 | TRANSPARENCY AND FLEXIBILITY, REFRACTIVE INDEX, CAN BE INSERTED FROM A SMALL INCISION | MENICON CO. LTD (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6242551-B1 | SUCH AS CONTACT LENSES, INTRAOCULAR LENSES, AND ARTIFICIAL CORNEA; REDUCES SEPARATION OR ELUTION, CHEMICALLY STABLE, AND DOES NOT DENATURE UNDER HYDROLYSIS; MAINTAINS ORIGINAL COLOR TONE | MENICON CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1030194-A1 | Material for a soft intraocular lens | Menicon Co., Ltd. (JP) | 2000-08-23 | — | — | EP | disclosed |