SCHEMBL7628151

SCHEMBL7628151

CC(COCC=C(Cl)Cl)COc1c(Cl)cc(O)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 2/20 0.33
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635381 0.88 HTT (0.35) SCN4A
SCHEMBL7637717 0.86 SCN4A (0.30) SCN4A
SCHEMBL7637710 0.86 SCN4A (0.30) SCN4A
SCHEMBL8405525 0.78 HSD17B10 (0.38) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7631608 0.78 PLAU (0.34) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7637679 0.77 PLAU (0.33) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7629390 0.77 HPGD (0.33) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7632977 0.77 CYP3A4 (0.31) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7632972 0.77 CYP3A4 (0.31) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7638412 0.75 PLAU (0.33) CYP3A4HPGDCRHBPCRHR2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888270-B1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2002-04-17 EP disclosed
US-6140274-A Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed
EP-0888270-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-01-07 EP disclosed
WO-1997028112-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-07 WO disclosed