Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 0.73 |
| ▸ | DRD2 | P14416 | 15/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903337 | 1.00 | DRD4 (0.73) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL7556929 | 0.91 | DRD4 (0.74) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL5419042 | 0.91 | DRD4 (0.74) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL14533026 | 0.88 | DRD4 (0.85) | DRD4DRD2HTR1AHTR2A | |
| SCHEMBL5414093 | 0.88 | DRD4 (0.85) | DRD4DRD2HTR1AHTR2A | |
| SCHEMBL5403039 | 0.88 | DRD4 (0.69) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL5417646 | 0.87 | DRD4 (0.73) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL6906393 | 0.87 | DRD4 (0.70) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL7632544 | 0.87 | DRD4 (0.70) | DRD4DRD2HTR1AHTR2AADORA2A | |
| SCHEMBL6846749 | 0.87 | DRD4 (0.73) | DRD4DRD2HTR1AHTR2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213031-A2 | Combination treatment for depression, anxiety and psychosis comprising an antidepressant and/or anxiolytic and a D4 receptor antagonist | Pfizer Products Inc. (US) | 2002-06-12 | — | — | EP | disclosed |