Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 19/20 | 0.61 |
| ▸ | TCF4 | P15884 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899926 | 0.92 | CYP3A4 (0.68) | CYP3A4 | |
| SCHEMBL10292458 | 0.92 | CYP3A4 (0.68) | CYP3A4 | |
| SCHEMBL13028883 | 0.89 | CYP3A4 (0.67) | CYP3A4 | |
| SCHEMBL10291369 | 0.88 | CYP3A4 (0.58) | CYP3A4TCF4CTNNB1 | |
| SCHEMBL13028822 | 0.88 | CYP3A4 (0.60) | CYP3A4TCF4CTNNB1 | |
| SCHEMBL2894885 | 0.88 | CYP3A4 (0.67) | CYP3A4 | |
| SCHEMBL750416 | 0.88 | CYP3A4 (0.67) | CYP3A4 | |
| SCHEMBL2894978 | 0.86 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL13354127 | 0.86 | CYP3A4 (0.61) | CYP3A4TCF4CTNNB1 | |
| SCHEMBL762363 | 0.86 | CYP3A4 (0.66) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138337-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-03-20 | — | — | US | disclosed |
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |