Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626931 | 1.00 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7620032 | 1.00 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7624212 | 1.00 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7621567 | 0.90 | POLB (0.54) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7623831 | 0.90 | POLB (0.54) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7622346 | 0.90 | POLB (0.54) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7626001 | 0.90 | POLB (0.54) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7618695 | 0.89 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7620019 | 0.89 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 | |
| SCHEMBL7617754 | 0.89 | POLB (0.53) | POLBNR1I2ALBPDE4DABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444656-B1 | (5R)-(2-AMINO-6-HYDROXY-PURIN-9-YLMETHYL)-(4R)-AZIDO-TETRAHYDR O-FURAN-(2S)- PHOSPHONATE; PARTICULARLY AGAINST HIV AND/OR HBV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-09-03 | — | — | US | claimed |
| US-6444656-B1 | (5R)-(2-AMINO-6-HYDROXY-PURIN-9-YLMETHYL)-(4R)-AZIDO-TETRAHYDR O-FURAN-(2S)- PHOSPHONATE; PARTICULARLY AGAINST HIV AND/OR HBV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-09-03 | — | — | US | disclosed |