Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 14/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.59 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637464 | 0.94 | HDAC3 (0.58) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7636474 | 0.92 | HDAC3 (0.56) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7610493 | 0.92 | HDAC3 (0.70) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7639631 | 0.91 | HDAC3 (0.55) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7578972 | 0.91 | HDAC3 (0.55) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7638094 | 0.91 | HDAC3 (0.60) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7581081 | 0.90 | HDAC3 (0.59) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7632476 | 0.90 | HDAC3 (0.54) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7640160 | 0.90 | HDAC3 (0.54) | HDAC3HDAC1HDAC6TOP1GLA | |
| SCHEMBL7637180 | 0.90 | HDAC3 (0.54) | HDAC3HDAC1HDAC6TOP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062340-A1 | HIGHLY LIPOPHILIC CAMPTOTHECIN PRODRUGS, METHODS OF PREPARATION, AND FORMULATIONS THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2002-08-15 | — | — | WO | disclosed |