⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883242 | 0.67 | — | — | |
| SCHEMBL447933 | 0.65 | — | — | |
| SCHEMBL5613441 | 0.65 | — | — | |
| SCHEMBL20955836 | 0.62 | — | — | |
| SCHEMBL11204404 | 0.62 | — | — | |
| SCHEMBL7863854 | 0.62 | — | — | |
| SCHEMBL22597647 | 0.60 | — | — | |
| SCHEMBL10423301 | 0.60 | — | — | |
| SCHEMBL21985218 | 0.60 | — | — | |
| SCHEMBL3658527 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614616-A | Process for preparing 3β7β-dihydroxy-Δ5 -steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | claimed |
| EP-0051143-B1 | PROCESS FOR THE PREPARATION OF 3-BETA, 7-BETA-DIHYDROXY-DELTA-5 STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | claimed |
| US-4416985-A | Process for preparing 3β,7β-dihydroxy-Δ5 -steroids | SCHERING, AKTIENGESELLSCHAFT (DE) | 1983-11-22 | — | — | US | claimed |
| EP-0051143-A1 | Process for the preparation of 3-beta, 7-beta-dihydroxy-delta-5 steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | claimed |
| EP-0741716-B1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5821363-A | Antineoplastic use and pharmaceutical compositions containing them | PHARMACIA & UPJOHN COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0741716-A1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020582-A1 | Δ12,13-ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |
| EP-0163596-B1 | ESTRIOL ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-08-16 | — | — | EP | disclosed |
| EP-0273242-A2 | 2-Pyri(mi)dylthio-aryl ether | BAYER AG (DE) | 1988-07-06 | — | — | EP | disclosed |
| US-4681875-A | CONTRACEPTIVES, GYNECOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |
| US-4614616-A | Process for preparing 3β7β-dihydroxy-Δ5 -steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| US-4614616-A | Process for preparing 3β7β-dihydroxy-Δ5 -steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0163596-A1 | Estriol esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-12-04 | — | — | EP | disclosed |
| EP-0051143-B1 | PROCESS FOR THE PREPARATION OF 3-BETA, 7-BETA-DIHYDROXY-DELTA-5 STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4416985-A | Process for preparing 3β,7β-dihydroxy-Δ5 -steroids | SCHERING, AKTIENGESELLSCHAFT (DE) | 1983-11-22 | — | — | US | disclosed |
| US-4416985-A | Process for preparing 3β,7β-dihydroxy-Δ5 -steroids | SCHERING, AKTIENGESELLSCHAFT (DE) | 1983-11-22 | — | — | US | disclosed |
| EP-0051143-A1 | Process for the preparation of 3-beta, 7-beta-dihydroxy-delta-5 steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051143-A1 | Process for the preparation of 3-beta, 7-beta-dihydroxy-delta-5 steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |