Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7629273 | 1.00 | MAOB (0.57) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL17157564 | 0.88 | MAOB (0.52) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL17157566 | 0.88 | MAOB (0.52) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL290718 | 0.81 | AKR1C3 (0.62) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL290719 | 0.81 | AKR1C3 (0.62) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL17157614 | 0.80 | MAOB (0.59) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL8149850 | 0.80 | MAOB (0.57) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL8149848 | 0.80 | MAOB (0.57) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL17157612 | 0.80 | MAOB (0.59) | MAOBMAOAVCPPRMT1AKR1C3 | |
| SCHEMBL31528750 | 0.79 | MAOB (0.56) | MAOBMAOAVCPPRMT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194429-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078768-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |