Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.64 |
| ▸ | CNR2 | P34972 | 7/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738485 | 0.87 | CNR1 (0.68) | CNR1CNR2ACHE | |
| SCHEMBL764490 | 0.86 | CNR1 (0.70) | CNR1CNR2ACHE | |
| SCHEMBL739526 | 0.84 | CNR1 (0.64) | CNR1CNR2ACHE | |
| SCHEMBL6333070 | 0.80 | CNR1 (0.59) | CNR1CNR2ACHE | |
| SCHEMBL6337279 | 0.79 | CNR1 (0.64) | CNR1CNR2ACHE | |
| SCHEMBL6342015 | 0.79 | CNR1 (0.66) | CNR1CNR2ACHE | |
| SCHEMBL762432 | 0.79 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL28779646 | 0.77 | CNR1 (0.68) | CNR1CNR2ACHE | |
| SCHEMBL6335075 | 0.77 | CNR1 (0.66) | CNR1CNR2ACHE | |
| SCHEMBL763028 | 0.77 | CNR1 (0.55) | CNR1CNR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138174-B2 | Such as N-{1-[7-(2-amino-ethoxyimino)-7-[4-(trifluoromethyl)phenyl]heptylamino]-1-[3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl]-methylidene)-4-chloro-benzenesulfonamide; pain. psychosis, anxiety, depression, attention deficits, cognitive disorders, obesity; neurodegenerative disorders | SOLVAY PHARMACEUTICALS B.V. (NL) | 2012-03-20 | — | — | US | disclosed |