SCHEMBL7630494

SCHEMBL7630494

C=C[Si](C)(C)c1ccc(C(=O)OO[C]2CC(C)CCC2C(C)C)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636521 0.92 NPC1 (0.31) NPC1L3MBTL1
SCHEMBL7633622 0.88 NPC1 (0.33) NPC1L3MBTL1
SCHEMBL7635017 0.87 NR1H2 (0.32)
SCHEMBL7633848 0.87
SCHEMBL7631181 0.87
SCHEMBL7636551 0.82 SCN1A (0.40) NPC1L3MBTL1
SCHEMBL7632747 0.81 KMT2A (0.41) NPC1
SCHEMBL7629934 0.81 POLB (0.41) NPC1L3MBTL1
SCHEMBL7629368 0.81 NPC1 (0.47) NPC1L3MBTL1
SCHEMBL7627330 0.80 MEN1 (0.38) NPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed