Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759172 | 0.92 | AURKA (0.84) | AURKAAURKB | |
| SCHEMBL764167 | 0.92 | AURKA (0.84) | AURKAAURKB | |
| SCHEMBL30634171 | 0.91 | AURKB (1.00) | AURKAAURKB | |
| SCHEMBL756739 | 0.91 | AURKB (1.00) | AURKAAURKB | |
| SCHEMBL10063835 | 0.88 | AURKA (0.81) | AURKAAURKB | |
| SCHEMBL757438 | 0.83 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL763393 | 0.83 | AURKA (0.73) | AURKAAURKB | |
| SCHEMBL13399811 | 0.83 | AURKA (0.71) | AURKAAURKB | |
| SCHEMBL759931 | 0.83 | AURKA (0.77) | AURKAAURKB | |
| SCHEMBL756769 | 0.82 | AURKA (1.00) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138194-B2 | Fused bicyclic pyrimidine compounds as aurora kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2012-03-20 | — | — | US | disclosed |